MP350 Microlyser™
Microfluidics | Cell Disruption
Cells are the basic building blocks of all living things. From bacterial cells like E. Coli, to yeast cells like Pichia pastoris to algae cells and others, proteins play vital roles in scientific breakthroughs such as gene therapy and vaccine production. The key to recovering the intracellular content is through the important process of cell lysis. This is the process of breaking cell membranes to recover the intracellular content.
Cell Disruption Challenges facing Traditional Methods
Traditional mechanical methods of production scale cell disruption have always presented significant challenges including:
- Inconsistent Shear Rates which create varying quality of results.
- Multiple Passes needed to achieve the desired levels which increases production times and risks damage to yields.
- Heat Regulation Challenges which can compromise the integrity of temperature-sensitive contents.
- Frequent Part Failures which can produce additional downtime and higher maintenance costs.
- Inefficient Separation which inhibits filtration and may cause clogging.
- Extensive Cleaning causing increased downtime and risk of contamination.
To address these challenges, Microfluidics International Corporation has a solution:
The MP350 Microlyser™ Processor
A New Innovation in Production Scale Biotech Cell Disruption Processing
The MP350 enhanced biopharma grade Microlyser™ processor is uniquely designed to overcome some of cell disruption's most complex production scale manufacturing issues. This remarkable production scale processor employs Microfluidics' proprietary Interaction Chamber™ technology with a patented sanitary electric pumping system, to deliver industry-leading production scale cell disruption yields.
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